Airway Hyperresponsiveness: From Molecules to Bedside Invited Review: Airway wall remodeling: friend or foe?
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چکیده
McParland, Brent E., Peter T. Macklem, and Peter D. Paré. Invited Review: Airway wall remodeling: friend or foe? J Appl Physiol 95: 426–434, 2003;10.1152/japplphysiol.00159.2003.—Airway wall remodeling is well documented for asthmatic airways and is believed to result from chronic and/or short-term exposure to inflammatory stimuli. Airway wall remodeling can contribute to airway narrowing as well as to the airway hyperresponsiveness, which is a characteristic abnormality in asthma. However, the potential for airway narrowing could be much worse if it were not for some of the protective effects of remodeling that may help to limit airway narrowing in asthmatic patients. This minireview discusses the evidence for airway wall remodeling and its effects, friend and/or foe, on airway narrowing in asthmatic patients.
منابع مشابه
Airway Hyperresponsiveness: From Molecules to Bedside Invited Review: Complexity of factors modulating airway narrowing in vivo: relevance to assessment of airway hyperresponsiveness
Brusasco, Vito, and Riccardo Pellegrino. Invited Review: Complexity of factors modulating airway narrowing in vivo: relevance to assessment of airway hyperresponsiveness. J Appl Physiol 95: 1305–1313, 2003;10.1152/japplphysiol.00001.2003.—In vivo, the airway response to constrictor stimuli is the net result of a complex array of factors, some facilitating and some opposing airway narrowing, whi...
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